How to find extended-spectrum beta-lactamase genes?

I recently ran RGI on some gut microbiome samples, and I wanted to compare the prevalence of extended spectrum beta-lactamase (ESBL) genes between some of the groups in my study.

This wasn’t listed directly in the RGI output, so I needed to add that info in.

I asked around and found 3 solutions:

  1. The information is listed in the card.json file that you can access following these download instructions. If you’re not familiar with json files, you can get a “pretty” view of that file by running `python -m json.tool card.json`, or there are some online json viewers. h/t @torsten
  2. You can get the information from the NCBI pathogen portal here. h/t Michael Feldgarden
  3. Or, you can download the info (either by just copy paste, or by web-scraping, there doesn’t appear to be a download option) from the Beta-lactamase database.

Easy!

One thought on “How to find extended-spectrum beta-lactamase genes?

  1. Pingback: Links 8/31/23 | Mike the Mad Biologist

Leave a comment