Annotating phylogenetic trees with gene presence/absence etc

As a bioinformatician, I spend a lot of time generating, interpreting and presenting trees. One of the most powerful ways to get some added value out of a tree is to be able to compare the phylogeny with the accessory gene content, to see if there is something going on with the mobile genetic elements that…

Thoughts on bioinformatics as wet-lab kits

I have just read Sean Eddy’s thought provoking blog post on the problems with how biology is handling high throughput sequencing which you should definitely read. One of his themes is that bioinformatics is going to be a key part of the 21st century biologists toolkit, and that biologists doing sequencing experiments should be able to tinker…